Sugi Predict

Sugi Predict / Compounds / SCHEMBL29669271

SCHEMBL29669271

SCHEMBL29669271

COC[C@H]1C[C@@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 2/20 0.41
▸ HSD11B1 P28845 1/20 0.40
▸ MCL1 Q07820 5/20 0.39
▸ CYP1A2 P05177 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ MMP13 P45452 1/20 0.38
▸ GPR119 Q8TDV5 7/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ NR1H2 P55055 1/20 0.36
▸ NR1H3 Q13133 1/20 0.36
▸ F13A1 P00488 1/20 0.36
▸ TGM2 P21980 1/20 0.36
▸ TGM1 P22735 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015585 0.94 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1366652 0.94 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL29105266 0.94 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1366650 0.94 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL29765023 0.94 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1441004 0.91 CYP2D6 (0.38) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1441007 0.91 CYP2D6 (0.38) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL12460550 0.90 CYP2D6 (0.39) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1541455 0.89 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB
SCHEMBL1543877 0.89 CYP2D6 (0.42) CYP2D6HSD11B1MCL1CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 — — US disclosed
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases KHORA SPV 1, LLC (US) 2025-06-17 — — US disclosed
CN-116057045-A Fibroblast growth factor receptor kinase inhibitors 金耐特生物制药公司 2023-05-02 — — CN disclosed
EP-4161656-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES Kinnate Biopharma Inc. (US) 2023-04-12 — — EP disclosed
US-20230078839-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1, LLC 2023-03-16 — — US disclosed
US-11345681-B1 Inhibitors of fibroblast growth factor receptor kinases KINNATE BIOPHARMA INC. (US) 2022-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 CYP2D6 4593/4885HSD11B1 3028/4885MCL1 522/4885
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 CYP2D6 4593/4885HSD11B1 3028/4885MCL1 522/4885
US-11345681-B1 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 CYP2D6 4593/4885HSD11B1 3028/4885MCL1 522/4885
US-20230078839-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 CYP2D6 4593/4885HSD11B1 3028/4885MCL1 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.