Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714999 | 0.92 | CA12 (0.44) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1714987 | 0.89 | CA12 (0.46) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1715922 | 0.85 | CA12 (0.45) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1715483 | 0.85 | NPC1 (0.50) | NPC1RAB9APTGS2EGFRHDAC1 | |
| SCHEMBL1715559 | 0.83 | NPC1 (0.48) | NPC1RAB9APTGS2EGFRHDAC1 | |
| SCHEMBL1715095 | 0.82 | SIGMAR1 (0.42) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL1715661 | 0.80 | NPC1 (0.47) | NPC1RAB9APTGS2EGFRHDAC1 | |
| SCHEMBL1715727 | 0.79 | PPARA (0.51) | NPC1RAB9APTGS2EGFRLMNA | |
| SCHEMBL1715532 | 0.78 | NPC1 (0.45) | NPC1RAB9APTGS2EGFRHDAC1 | |
| SCHEMBL1715285 | 0.76 | CYP1A2 (0.46) | NPC1RAB9APTGS2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |