Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.56 |
| ▸ | HRH2 | P25021 | 6/20 | 0.56 |
| ▸ | HRH1 | P35367 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622767 | 0.82 | HRH3 (0.50) | HRH3HRH2HRH1RAB9AMEN1 | |
| SCHEMBL12460718 | 0.80 | HRH3 (0.48) | HRH3HRH2HRH1 | |
| SCHEMBL16569508 | 0.80 | HRH3 (0.54) | HRH3HRH2HRH1MEN1KMT2A | |
| SCHEMBL1713974 | 0.80 | HRH3 (0.46) | HRH3HRH2HRH1RAB9AMEN1 | |
| SCHEMBL1715355 | 0.76 | HRH3 (0.71) | HRH3HRH2HRH1 | |
| SCHEMBL1715453 | 0.75 | HRH3 (0.50) | HRH3HRH2HRH1MEN1KMT2A | |
| SCHEMBL17975502 | 0.75 | HRH3 (0.61) | HRH3HRH2HRH1 | |
| SCHEMBL15033035 | 0.74 | HRH3 (0.71) | HRH3RAB9AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL14469175 | 0.74 | HRH3 (0.67) | HRH3RAB9AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL14528025 | 0.73 | HRH3 (0.53) | HRH3HRH2HRH1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |