Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.48 |
| ▸ | HRH2 | P25021 | 8/20 | 0.48 |
| ▸ | HRH1 | P35367 | 8/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460719 | 0.80 | HRH3 (0.56) | HRH3HRH2HRH1 | |
| SCHEMBL7823918 | 0.79 | LSS (0.48) | HRH3SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL1715204 | 0.77 | MMP2 (0.41) | HRH3HRH2HRH1SLC6A2SLC6A4 | |
| SCHEMBL492168 | 0.76 | CACNA1B (0.66) | HRH3SLC6A4LSSCACNA1BCACNA1H | |
| SCHEMBL2338542 | 0.76 | SLC6A2 (0.57) | HRH3HRH2HRH1SLC6A2SLC6A4 | |
| SCHEMBL6653536 | 0.75 | LSS (0.53) | HRH3SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL12460736 | 0.75 | CACNA1B (0.53) | HRH3HRH2HRH1CACNA1BCACNA1H | |
| SCHEMBL13437933 | 0.74 | ADRB1 (0.47) | HRH3LSSHTR3AKCNH2KDM1A | |
| SCHEMBL22878508 | 0.74 | SLC6A2 (0.47) | HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1714172 | 0.74 | SLC6A2 (0.58) | HRH3HRH2HRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |