Toluene

Toluene

SCHEMBL124611

Cc1ccccc1.O=C(O)Cl

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
TSHR P16473 2/20 0.65
ALOX12 P18054 1/20 0.65
ACHE P22303 1/20 0.65
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 2/20 0.45
AKR1C3 P42330 1/20 0.45
POLB P06746 1/20 0.43
SRD5A2 P31213 1/20 0.42
PTGS2 P35354 1/20 0.42
CYP1B1 Q16678 1/20 0.42
VCP P55072 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL4861938 1.00 LMNA (0.65) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL1850918 0.94 LMNA (0.65) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL5127452 0.92 LMNA (0.61) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL4369643 0.92 LMNA (0.61) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL27555376 0.89 LMNA (0.58) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL7355317 0.88 LMNA (0.73) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL27369787 0.88 LMNA (0.73) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL2914390 0.88 LMNA (0.73) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL48134 0.88 LMNA (0.73) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL5776784 0.85 LMNA (0.69) LMNATSHRALOX12ACHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187867-B1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GEN ELECTRIC (US) 2005-08-17 EP claimed
US-6664366-B2 Interfacial polymerization of a 1,3-dihydroxybenzene moiety and aromatic dicarboxylic acid moieties to create polyesters free of anhydride linkages GENERAL ELECTRIC COMPANY 2003-12-16 US claimed
US-6596843-B2 Interfacial method for preparing polymers comprising resorcinol arylate polyester chain members substantially free of anhydride linkages GENERAL ELECTRIC COMPANY 2003-07-22 US claimed
JP-2002544352-A 2002-12-24 JP claimed
US-20020156229-A1 Thermally stable polymers, method of preparation, and articles made therefrom GENERAL ELECTRIC COMPANY 2002-10-24 US claimed
US-20020039657-A1 Thermally stable polymers, method of preparation, and articles, made therefrom GENERAL ELECTRIC COMPANY 2002-04-04 US claimed
EP-1187867-A1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-03-20 EP claimed
US-6294647-B1 COMBINING RESORCINOL COMPOUND AND CATALYST IN MIXTURE OF WATER AND SOLVENTIMMISCIBLE WITH WATER; ADDING DICARBOXYLIC ACID DICHLORIDE IN PRESENCE OF AN ACID ACCEPTOR TO PRODUCE POLYESTER GENERAL ELECTRIC COMPANY 2001-09-25 US claimed
WO-2000069945-A1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2000-11-23 WO claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
EP-4247890-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECH BV (NL) 2026-05-13 EP disclosed
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4305105-B1 THERMOPLASTIC COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2026-02-18 EP disclosed
US-20010016626-A1 Weatherable block copolyestercarbonate compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-08-23 US disclosed
EP-1124879-A1 WEATHERABLE BLOCK COPOLYESTERCARBONATES, METHODS FOR THEIR PREPARATION AND BLENDS CONTAINING THEM GENERAL ELECTRIC COMPANY (US) 2001-08-22 EP disclosed
US-6265522-B1 RESORCINOL ACRYLATE POLYESTER GENERAL ELECTRIC COMPANY 2001-07-24 US disclosed
US-6229020-B1 REACTING N-SUCCINIMIDYL AND P-NITROPHENYL CINNAMATE DERIVATIVES WITH PHYSIOLOGICALLY ACTIVE SUBSTANCE SUCH AS AN AMINO ACID; PROTECTING AMINO OR HYDROXY GROUPS FOR ANALYSIS OF BIOLOGICAL REACTIONS BY IRRADIATION WITH LIGHT LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-05-08 US disclosed
WO-2000069945-A1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2000-11-23 WO disclosed
WO-2000026275-A1 WEATHERABLE BLOCK COPOLYESTERCARBONATES, METHODS FOR THEIR PREPARATION AND BLENDS CONTAINING THEM GENERAL ELECTRIC COMPANY (US) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA LMNA 1268/4885TSHR 3048/4885ALOX12 3524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.