⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27854432 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL16912719 | 0.87 | TSHR (0.54) | — | |
| Dimethyl Succinate SCHEMBL10213 | 0.85 | TSHR (1.00) | — | |
| Dimethyl Succinate SCHEMBL28054469 | 0.85 | TSHR (1.00) | — | |
| SCHEMBL642929 | 0.84 | TSHR (0.67) | — | |
| SCHEMBL48697 | 0.84 | TSHR (0.75) | — | |
| SCHEMBL719374 | 0.82 | TSHR (0.64) | — | |
| SCHEMBL7408161 | 0.82 | TSHR (0.64) | — | |
| SCHEMBL4204017 | 0.82 | TSHR (0.64) | — | |
| SCHEMBL19141 | 0.82 | TSHR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025604-A9 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-05-02 | — | — | WO | claimed |
| WO-2024025604-A2 | DEVELOPMENT OF AN ENZYME-INHIBITOR REACTION USING CELLULAR RETINOIC ACID BINDING PROTEIN II FOR ONE-POT MEGAMOLECULE ASSEMBLY | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | claimed |
| CN-112645926-B | Sertraline derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-12-13 | — | — | CN | claimed |
| CN-112645926-A | Sertraline derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2021-04-13 | — | — | CN | claimed |
| EP-1841747-B1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2012-09-05 | — | — | EP | claimed |
| US-20090209596-A1 | Oxazole Hydroxamic Acid Derivatives and Use Thereof | SK HOLDINGS CO., LTD | 2009-08-20 | — | — | US | claimed |
| EP-1841747-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK Corporation (KR) | 2007-10-10 | — | — | EP | claimed |
| WO-2006075888-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK CORPORATION (KR) | 2006-07-20 | — | — | WO | claimed |
| EP-0532328-A2 | Novel lignans, intermediates thereof and a process for preparing the intermediates | TSUMURA & CO. (JP) | 1993-03-17 | — | — | EP | claimed |
| EP-0440329-A1 | S-substituted carbonyl substituted betathioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-08-07 | — | — | EP | claimed |
| JP-5086046-A | — | — | None | — | — | JP | disclosed |
| JP-9110740-A | — | — | None | — | — | JP | disclosed |
| JP-5070402-A | — | — | None | — | — | JP | disclosed |
| CN-122055150-A | Cyproheptadine derivatives | 思凯生科股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4725560-A2 | ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2026-04-15 | — | — | EP | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3989689-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3949081-A | 4-Carbamoyl-1-benzazepines as antiinflammatory agents | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3934027-A | 18β-Glycyrrhetinic acid amides useful as antiulcer agents | PFIZER INC. (US) | 1976-01-20 | — | — | US | disclosed |