SCHEMBL19141

SCHEMBL19141

COC(=O)CCCCCCC(=O)Cl

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.55
TP53 P04637 1/20 0.48
KAT2B Q92831 3/20 0.46
KMT2A Q03164 2/20 0.46
RECQL P46063 1/20 0.45
EPHX2 P34913 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2527082 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL7407458 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL4204017 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL719374 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL7408161 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL989611 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL9353850 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL642929 0.98 TSHR (0.67) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL48697 0.93 TSHR (0.75) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL3502791 0.87 TSHR (0.82) TSHRALDH1A1LMNAKMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102197-A1 METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF UNRAVEL BIOSCIENCES, INC. (US) 2026-05-15 WO claimed
US-20260125343-A1 METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF UNRAVEL BIOSCIENCES INC (US) 2026-05-07 US claimed
CN-117624208-B Fluorescent probe for targeting liver cancer cells and preparation method and application thereof 临沂大学 2024-07-12 CN claimed
CN-117624208-A Fluorescent probe for targeting liver cancer cells and preparation method and application thereof 临沂大学 2024-03-01 CN claimed
EP-1841747-B1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2012-09-05 EP claimed
US-20120053188-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE(TGEN (US) 2012-03-01 US claimed
US-20090209596-A1 Oxazole Hydroxamic Acid Derivatives and Use Thereof SK HOLDINGS CO., LTD 2009-08-20 US claimed
WO-2009100045-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2009-08-13 WO claimed
EP-1841747-A1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK Corporation (KR) 2007-10-10 EP claimed
WO-2006075888-A1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK CORPORATION (KR) 2006-07-20 WO claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
US-4052407-A ENZYME INHIBITORS, MULTISTAGE GYOGYSZERKUTATO INTEZET (HU) 1977-10-04 US claimed
CN-122055150-A Cyproheptadine derivatives 思凯生科股份有限公司 2026-05-15 CN disclosed
WO-2026102197-A1 METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF UNRAVEL BIOSCIENCES, INC. (US) 2026-05-15 WO disclosed
US-20260125343-A1 METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF UNRAVEL BIOSCIENCES INC (US) 2026-05-07 US disclosed
US-20250304549-A1 HYDROXYAMIDE DERIVATIVE AND USE THEREOF SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) 2025-10-02 US disclosed
US-4097504-A 11,12-Secoprostaglandins MERCK & CO., INC. (US) 1978-06-27 US disclosed
US-4092356-A 11,12-Secoprostaglandins MERCK & CO., INC. (US) 1978-05-30 US disclosed
US-4066692-A 11,12-SECOPROSTAGLANDINS MERCK & CO., INC. (US) 1978-01-03 US disclosed
US-4052407-A ENZYME INHIBITORS, MULTISTAGE GYOGYSZERKUTATO INTEZET (HU) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053188-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES HDAC5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC4 TSHR 3959/4885ALDH1A1 863/4885LMNA 1006/4885
US-20090209596-A1 Oxazole Hydroxamic Acid Derivatives and Use Thereof HDAC1, HDAC5, HDAC7 TSHR 4146/4885ALDH1A1 424/4885LMNA 3307/4885
US-20260125343-A1 METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF HDAC8, HDAC7, SUB1 TSHR 2908/4885ALDH1A1 522/4885LMNA 1860/4885
US-20250304549-A1 HYDROXYAMIDE DERIVATIVE AND USE THEREOF HDAC1, HDAC11, HDAC5 TSHR 3472/4885ALDH1A1 387/4885LMNA 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.