Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246509 | 0.99 | CHAT (0.52) | CHATRAD52APPPKMHTT | |
| SCHEMBL1245863 | 0.92 | CHAT (0.57) | CHATRAD52APPPKMHTT | |
| Hydrochloric Acid SCHEMBL1244769 | 0.82 | CHAT (0.51) | CHATRAD52APPPKMHTT | |
| SCHEMBL1245684 | 0.80 | CHAT (0.53) | CHATRAD52APPPKMHTT | |
| Hydrochloric Acid SCHEMBL1246932 | 0.80 | CHAT (0.53) | CHATRAD52APPPKMHTT | |
| SCHEMBL1245825 | 0.79 | CHAT (0.49) | CHATRAD52APPPKMHTT | |
| SCHEMBL1245835 | 0.78 | CHAT (0.59) | CHATRAD52APPPKMHTT | |
| Hydrochloric Acid SCHEMBL1246494 | 0.77 | BACE1 (0.56) | CHATRAD52APPPKMHTT | |
| Hydrochloric Acid SCHEMBL1246670 | 0.77 | CHAT (0.57) | CHATRAD52APPPKMHTT | |
| Alanine SCHEMBL27855847 | 0.77 | CHAT (0.64) | CHATRAD52APPPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | claimed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | claimed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | claimed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | disclosed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122135-A1 | Novel Peptidase Substrates | CPN1, CTRL, ANPEP | CHAT 1696/4885RAD52 4505/4885APP 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.