Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1246932 | 0.89 | CHAT (0.53) | CHATAPPRAD52LTA4HPKM | |
| SCHEMBL1245825 | 0.88 | CHAT (0.49) | CHATAPPRAD52PKMHTT | |
| SCHEMBL1245828 | 0.86 | CHAT (0.53) | CHATAPPRAD52LTA4HPKM | |
| SCHEMBL1245827 | 0.86 | LTA4H (0.48) | CHATRAD52LTA4HPKMHTT | |
| Hydrochloric Acid SCHEMBL1244769 | 0.85 | CHAT (0.51) | CHATAPPRAD52PKMHTT | |
| SCHEMBL1245863 | 0.85 | CHAT (0.57) | CHATAPPRAD52LTA4HPKM | |
| Hydrochloric Acid SCHEMBL1246494 | 0.82 | BACE1 (0.56) | CHATAPPRAD52PKMHTT | |
| Hydrochloric Acid SCHEMBL1244753 | 0.81 | CHAT (0.53) | CHATAPPRAD52LTA4HPKM | |
| SCHEMBL1246509 | 0.80 | CHAT (0.52) | CHATAPPRAD52LTA4HPKM | |
| SCHEMBL1246159 | 0.80 | CHAT (0.51) | CHATAPPRAD52LTA4HPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |