Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714925 | 0.88 | KDR (0.45) | HTTSMN1; SMN2NPSR1KDRFLT1 | |
| SCHEMBL5718691 | 0.85 | KDR (0.46) | HTTSMN1; SMN2NPSR1KDRFLT1 | |
| SCHEMBL1715868 | 0.85 | KDR (0.46) | HTTSMN1; SMN2NPSR1KDRFLT1 | |
| SCHEMBL12461795 | 0.76 | ADRA2C (0.37) | HTTSMN1; SMN2NPSR1ADRA2CKDR | |
| SCHEMBL5718588 | 0.74 | KDR (0.46) | HTTSMN1; SMN2NPSR1ADRA2CKDR | |
| SCHEMBL1715032 | 0.74 | KDR (0.46) | HTTSMN1; SMN2NPSR1ADRA2CKDR | |
| SCHEMBL12461049 | 0.73 | KDM4E (0.43) | HTTSMN1; SMN2NPSR1ADRA2CKDR | |
| SCHEMBL1715244 | 0.73 | KDR (0.47) | ADRA2CKDRFLT1ALDH1A1 | |
| SCHEMBL1715288 | 0.72 | KIT (0.53) | GRM4KDM4EALDH1A1 | |
| SCHEMBL1715524 | 0.72 | KDR (0.47) | ADRA2CKDRFLT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |