Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714850 | 0.92 | PARP1 (0.49) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1715004 | 0.82 | PARP1 (0.47) | PARP1KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL1716299 | 0.77 | KDM4E (0.42) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1715786 | 0.77 | PPM1D (0.42) | PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL1714832 | 0.72 | HDAC1 (0.40) | PARP1ALDH1A1HDAC1 | |
| SCHEMBL7760861 | 0.69 | L3MBTL1 (0.56) | ALDH1A1MAPTKMT2A | |
| SCHEMBL1715097 | 0.65 | KIT (0.51) | — | |
| SCHEMBL1715244 | 0.64 | KDR (0.47) | ALDH1A1 | |
| SCHEMBL12461842 | 0.64 | CYP19A1 (0.38) | KDM4E | |
| SCHEMBL1715901 | 0.64 | AOC3 (0.41) | PARP1KDM4EALDH1A1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |