SCHEMBL12463164

SCHEMBL12463164

Cc1cc(=O)nc(NC(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 8/20 0.37
▸ ATM Q13315 2/20 0.37
▸ SSTR2 P30874 8/20 0.37
▸ NPSR1 Q6W5P4 6/20 0.36
▸ POLB P06746 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ MAPT P10636 5/20 0.36
▸ KDM4E B2RXH2 3/20 0.36
▸ SSTR1 P30872 1/20 0.34
▸ SSTR4 P31391 1/20 0.34
▸ SSTR3 P32745 1/20 0.34
▸ SSTR5 P35346 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21122927 0.86 P2RY12 (0.35) TDP1ATMNPSR1POLBMAPT
SCHEMBL12463168 0.86 P2RY12 (0.35) TDP1ATMNPSR1POLBMAPT
SCHEMBL12462486 0.86 FOLH1 (0.45) —
SCHEMBL12374469 0.82 USP2 (0.40) —
SCHEMBL23912446 0.82 SSTR2 (0.39) TDP1ATMSSTR2NPSR1POLB
SCHEMBL21065264 0.80 TDP1 (0.43) TDP1ATMNPSR1POLBKMT2A
SCHEMBL21065266 0.80 TDP1 (0.43) TDP1ATMNPSR1POLBKMT2A
SCHEMBL522870 0.73 PAOX (0.39) —
SCHEMBL15978635 0.73 PAOX (0.39) —
SCHEMBL22590659 0.73 KDM4E (0.38) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2021-10-12 — — US disclosed
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2020-10-27 — — US disclosed
EP-2521530-B1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND OREAL (FR) 2019-06-26 — — EP disclosed
US-20130017162-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND L'OREAL (FR) 2013-01-17 — — US disclosed
WO-2011080494-A2 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND L'OREAL (FR) 2011-07-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130017162-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND KRT18, KIT, TYR TDP1 4164/4885ATM 1273/4885SSTR2 670/4885
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR TDP1 4164/4885ATM 1273/4885SSTR2 670/4885
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR TDP1 4164/4885ATM 1273/4885SSTR2 670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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