SCHEMBL23912446

SCHEMBL23912446

Cc1cc(=O)cc(NC(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 10/20 0.39
▸ TDP1 Q9NUW8 8/20 0.38
▸ ATM Q13315 2/20 0.38
▸ NPSR1 Q6W5P4 6/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ MAPT P10636 5/20 0.37
▸ KDM4E B2RXH2 3/20 0.37
▸ SSTR1 P30872 1/20 0.36
▸ SSTR4 P31391 1/20 0.36
▸ SSTR3 P32745 1/20 0.36
▸ SSTR5 P35346 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12463164 0.82 TDP1 (0.37) SSTR2TDP1ATMNPSR1KMT2A
SCHEMBL28269427 0.73 CPB2 (0.42) SSTR2TDP1ATMNPSR1KMT2A
SCHEMBL28620928 0.72 ATM (0.39) SSTR2TDP1ATMNPSR1KMT2A
SCHEMBL12462647 0.72 TDP1 (0.52) TDP1ATMNPSR1KMT2APOLB
SCHEMBL24630326 0.71 SLC6A5 (0.46) TDP1ATMKMT2APOLB
SCHEMBL10076057 0.71 SLC6A5 (0.40) TDP1ATMNPSR1KMT2APOLB
SCHEMBL24630329 0.71 SLC6A5 (0.46) TDP1ATMKMT2APOLB
SCHEMBL26241162 0.71 FOLH1 (0.42) SSTR2TDP1ATMNPSR1KMT2A
SCHEMBL23608150 0.71 CTSK (0.49) TDP1ATMNPSR1KMT2APOLB
SCHEMBL1304236 0.71 CTSK (0.49) TDP1ATMNPSR1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2021-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11141368-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR SSTR2 670/4885TDP1 4164/4885ATM 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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