Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.61 |
| ▸ | FAP | Q12884 | 5/20 | 0.61 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | PEPD | P12955 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243342 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10193698 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8126121 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25716270 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9966602 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26119597 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3726198 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL176690 | 0.86 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL176689 | 0.86 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12292668 | 0.83 | DPP4 (0.57) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295197-A1 | STAT5 and STAT6 Degraders and Uses Thereof | REGENTS OF THE UNIV OF MICHICAN (US) | 2023-09-21 | — | — | US | disclosed |
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |
| EP-1730142-B1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2011-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295197-A1 | STAT5 and STAT6 Degraders and Uses Thereof | STAT6, STAT5B, STAT5A | DPP4 351/4885DPP8 696/4885DPP9 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.