Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.61 |
| ▸ | FAP | Q12884 | 1/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 6/20 | 0.55 |
| ▸ | REN | P00797 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26119597 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8243342 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL3726198 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL176690 | 0.98 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL176689 | 0.98 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12463580 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8126121 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10193698 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL25716270 | 0.87 | DPP4 (0.61) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13019858 | 0.83 | PEPD (0.58) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| WO-2012082672-A2 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. (US) | 2012-06-21 | — | — | WO | disclosed |