Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 8/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140139 | 0.92 | CA12 (0.43) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL31201814 | 0.84 | TDP1 (0.44) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL3757130 | 0.84 | TDP1 (0.44) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL31041082 | 0.81 | MEN1 (0.39) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL9017483 | 0.80 | CA12 (0.42) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL14176776 | 0.80 | MEN1 (0.41) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL23801581 | 0.79 | CA12 (0.42) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL8140143 | 0.79 | MAOA (0.43) | MEN1KMT2AGAACA14CA12 | |
| SCHEMBL4798674 | 0.78 | EPHX2 (0.42) | TDP1 | |
| SCHEMBL4677852 | 0.77 | CA14 (0.44) | GAACA14CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |