Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059364 | 0.75 | F2 (0.42) | ATMMEN1KMT2AMAPTEGFR | |
| SCHEMBL22399181 | 0.75 | ATM (0.31) | ATM | |
| SCHEMBL19085495 | 0.74 | AKT1 (0.36) | ATMAKT1EGFRRECQL | |
| SCHEMBL26638297 | 0.72 | AKT1 (0.33) | AKT1 | |
| SCHEMBL19685232 | 0.72 | ATM (0.36) | ATMLMNAMAPTAKT1EGFR | |
| SCHEMBL26343073 | 0.71 | ATM (0.31) | ATM | |
| SCHEMBL18105407 | 0.70 | ATM (0.35) | ATMEGFRRECQL | |
| SCHEMBL25657095 | 0.70 | ATM (0.44) | ATMLMNANPSR1AKT1EGFR | |
| SCHEMBL20991479 | 0.70 | GRIN2B (0.37) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1071814 | 0.70 | AKT1 (0.38) | ATMMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |