SCHEMBL19085495

SCHEMBL19085495

C=C/N=C(\C=C/C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 1/20 0.36
▸ ATM Q13315 1/20 0.35
▸ EGFR P00533 2/20 0.32
▸ RECQL P46063 1/20 0.32
▸ PLA2G7 Q13093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685232 0.82 ATM (0.36) AKT1ATMEGFRRECQLPLA2G7
SCHEMBL23019810 0.81 MAPT (0.35) ATMEGFR
SCHEMBL23278775 0.81 HTT (0.35) —
SCHEMBL18105407 0.81 ATM (0.35) ATMEGFRRECQLPLA2G7
SCHEMBL18792377 0.81 AKT1 (0.36) AKT1ATMEGFRRECQL
SCHEMBL19773599 0.79 AKT1 (0.46) AKT1ATMEGFRRECQL
SCHEMBL12463754 0.74 ATM (0.33) AKT1ATMEGFRRECQL
SCHEMBL23079954 0.74 HCAR2 (0.38) —
SCHEMBL10292638 0.74 KDM4E (0.42) —
SCHEMBL25657095 0.73 ATM (0.44) AKT1ATMEGFRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3637490-A1 HIGH EFFICIENCY YELLOW LIGHT EMITTERS FOR OLED DEVICES Universal Display Corporation (US) 2020-04-15 — — EP disclosed
US-10186672-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-22 — — US disclosed
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10186672-B2 Organic electroluminescent materials and devices TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885EGFR 2119/4885
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885EGFR 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback