Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30885561 | 0.84 | CA2 (0.52) | CA1CA2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3515063 | 0.80 | CHRM1 (0.50) | CA2SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL13503305 | 0.80 | SLC1A2 (0.39) | CA1CA2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3515065 | 0.80 | CHRM1 (0.50) | CA2SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL13883453 | 0.80 | SLC1A2 (0.39) | CA1CA2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL13637318 | 0.80 | CHRM1 (0.50) | CA2SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL6433806 | 0.79 | — | — | |
| SCHEMBL3178870 | 0.78 | CA1 (0.40) | CA1CA2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL8234716 | 0.78 | CA1 (0.40) | CA1CA2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL2012397 | 0.78 | CA1 (0.40) | CA1CA2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985402-B2 | Ultrasound contrast agent of peptide monomers; peptide vectors having high KDR binding affinity; gas filled microvesicle containing a fluorinated gas and a phospholipid | BRACCO SUISSE SA (CH) | 2011-07-26 | — | — | US | disclosed |
| US-7794693-B2 | Peptide-phospholipid conjugate;ultrasound contrast agent compositions; imaging KDR-containing tissue, evaluating angiogenic processes associated with neoplastic conditions | BRACCO INTERNATIONAL B.V. (NL) | 2010-09-14 | — | — | US | disclosed |
| US-20090131636-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO INTERNATIONAL B.V. (NL) | 2009-05-21 | — | — | US | disclosed |
| US-20080152594-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO SUISSE SA (CH) | 2008-06-26 | — | — | US | disclosed |