Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20306714 | 0.90 | CA9 (0.55) | CA1CA9CA2CA4CA12 | |
| SCHEMBL15043752 | 0.87 | CA9 (0.58) | CA1CA9CA2CA4CA12 | |
| SCHEMBL19254187 | 0.84 | KDM4E (0.55) | CA1CA9CA2CA4KDM4E | |
| SCHEMBL12235644 | 0.83 | CA9 (0.56) | CA1CA9CA2CA4CA12 | |
| SCHEMBL22022263 | 0.82 | CA9 (0.53) | CA1CA9CA2CA4CA12 | |
| SCHEMBL19209393 | 0.81 | HSD17B10 (0.55) | CA1CA9CA2CA4CA12 | |
| SCHEMBL15043753 | 0.80 | NR1H3 (0.58) | CA1CA9CA2CA4CA12 | |
| SCHEMBL4473452 | 0.79 | CA9 (0.52) | CA1CA9CA2CA4CA12 | |
| SCHEMBL6230240 | 0.79 | CA9 (0.52) | CA1CA9CA2CA4CA12 | |
| SCHEMBL15043754 | 0.78 | CASP3 (0.51) | CA1CA9CA2CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005500-B1 | ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS | UNIV SOUTHERN CALIFORNIA (US) | 2011-07-06 | — | — | EP | disclosed |