SCHEMBL12464481

SCHEMBL12464481

NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H](N)CC1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MC5R P33032 2/20 0.59
MC1R Q01726 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12464198 1.00 MC5R (0.59) MC5RMC1R
SCHEMBL12464202 1.00 MC5R (0.59) MC5RMC1R
SCHEMBL12464482 0.95 MC5R (0.54) MC5RMC1R
SCHEMBL12464480 0.92 MC5R (0.51) MC5RMC1R
SCHEMBL12464359 0.89 MC5R (0.68) MC5RMC1R
SCHEMBL12464197 0.89 MC5R (0.68) MC5RMC1R
SCHEMBL12464195 0.89 MC5R (0.68) MC5RMC1R
SCHEMBL12464203 0.89
SCHEMBL12464476 0.84 MC5R (0.61) MC5RMC1R
SCHEMBL12464363 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110183358-A1 METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE THE BURNHAM INSTITUTE (US) 2011-07-28 US disclosed