Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.61 |
| ▸ | MC1R | Q01726 | 2/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 3/20 | 0.54 |
| ▸ | NPY2R | P49146 | 3/20 | 0.54 |
| ▸ | NPY4R | P50391 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464197 | 0.95 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464359 | 0.95 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464195 | 0.95 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464358 | 0.93 | NPY1R (0.59) | NPY1RNPY2RNPY4R | |
| SCHEMBL12464482 | 0.90 | MC5R (0.54) | MC5RMC1R | |
| SCHEMBL8896673 | 0.86 | NPY1R (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL8895453 | 0.86 | NPY1R (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL8896669 | 0.84 | GHSR (0.55) | NPY1RNPY2RNPY4R | |
| SCHEMBL12464202 | 0.84 | MC5R (0.59) | MC5RMC1R | |
| SCHEMBL12464481 | 0.84 | MC5R (0.59) | MC5RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |