Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 18/20 | 0.55 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398059 | 0.94 | BRAF (0.55) | BRAFABL1BCR | |
| SCHEMBL12465161 | 0.92 | BRAF (0.54) | BRAFABL1BCR | |
| SCHEMBL12398450 | 0.91 | BRAF (0.53) | BRAFABL1BCR | |
| SCHEMBL12397954 | 0.91 | BRAF (0.57) | BRAFABL1BCR | |
| SCHEMBL12397996 | 0.89 | BRAF (0.56) | BRAFABL1BCR | |
| SCHEMBL12398430 | 0.88 | BRAF (0.52) | BRAFABL1BCR | |
| SCHEMBL12397967 | 0.88 | BRAF (0.56) | BRAFABL1BCR | |
| SCHEMBL12398490 | 0.87 | CSF1R (0.48) | BRAFABL1BCR | |
| SCHEMBL12398227 | 0.87 | GPR142 (0.53) | BRAFABL1BCR | |
| SCHEMBL12465111 | 0.86 | BRAF (0.51) | BRAFABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | BRAF 525/4885ABL1 136/4885BCR 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.