Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 11/20 | 0.57 |
| ▸ | CSF1R | P07333 | 2/20 | 0.53 |
| ▸ | LYN | P07948 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | TEK | Q02763 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 4/20 | 0.52 |
| ▸ | BCR | P11274 | 4/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398123 | 0.92 | BRAF (0.57) | BRAFCSF1RLYNABL1BCR | |
| SCHEMBL12398296 | 0.89 | BRAF (0.54) | BRAFCSF1RLYNABL1BCR | |
| SCHEMBL12465027 | 0.88 | BRAF (0.51) | BRAFCSF1RLYNRAF1TEK | |
| SCHEMBL12465032 | 0.88 | BRAF (0.51) | BRAFCSF1RLYNRAF1TEK | |
| SCHEMBL12465029 | 0.87 | BRAF (0.49) | BRAFCSF1RLYNRAF1TEK | |
| SCHEMBL12465115 | 0.87 | ABL1 (0.58) | BRAFCSF1RLYNRAF1ABL1 | |
| SCHEMBL12465259 | 0.86 | BRAF (0.59) | BRAFCSF1RLYNRAF1TEK | |
| SCHEMBL12398294 | 0.86 | BRAF (0.54) | BRAFABL1BCR | |
| SCHEMBL12398247 | 0.85 | BRAF (0.56) | BRAFCSF1RLYNABL1BCR | |
| SCHEMBL12398134 | 0.85 | BRAF (0.59) | BRAFABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | BRAF 525/4885CSF1R 594/4885LYN 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.