Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 9/20 | 0.47 |
| ▸ | ABL1 | P00519 | 7/20 | 0.43 |
| ▸ | BCR | P11274 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465133 | 0.88 | BRAF (0.51) | GPR142BRAF | |
| SCHEMBL12465177 | 0.86 | GPR142 (0.44) | GPR142ABL1BCRKMT2A | |
| SCHEMBL12465361 | 0.86 | BRAF (0.49) | ABL1BCRBRAF | |
| SCHEMBL12465148 | 0.85 | BRAF (0.43) | GPR142ABL1BCRBRAFTEK | |
| SCHEMBL12465358 | 0.84 | BRAF (0.51) | ABL1BCRBRAF | |
| SCHEMBL12399168 | 0.83 | GPR142 (0.57) | GPR142ABL1BCRBRAF | |
| SCHEMBL12464991 | 0.82 | GPR142 (0.47) | GPR142ABL1BCRKDM4EMEN1 | |
| SCHEMBL12465317 | 0.81 | BRAF (0.49) | ABL1BCRBRAF | |
| SCHEMBL12399189 | 0.80 | GPR142 (0.50) | GPR142ABL1BCRBRAF | |
| SCHEMBL12465146 | 0.80 | GPR142 (0.42) | GPR142ABL1BCRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | GPR142 3760/4885ABL1 136/4885BCR 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.