Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 18/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465189 | 0.94 | BRAF (0.45) | BRAFRAF1 | |
| SCHEMBL12465270 | 0.93 | BRAF (0.44) | BRAFRAF1 | |
| SCHEMBL12465343 | 0.89 | TEK (0.52) | BRAFTEK | |
| SCHEMBL12465168 | 0.87 | BRAF (0.46) | BRAFRAF1 | |
| SCHEMBL12397504 | 0.85 | GPR142 (0.48) | BRAF | |
| SCHEMBL12465132 | 0.84 | GPR142 (0.43) | BRAF | |
| SCHEMBL13960414 | 0.83 | BRAF (0.40) | BRAF | |
| SCHEMBL12465269 | 0.82 | BRAF (0.45) | BRAFTEK | |
| SCHEMBL12465135 | 0.82 | ABL1 (0.48) | TEK | |
| SCHEMBL17612930 | 0.82 | BRAF (0.39) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | BRAF 525/4885RAF1 394/4885TEK 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.