Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465757 | 0.87 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL12465777 | 0.80 | MAPT (0.52) | MAPTKDM4EALDH1A1RAB9ALPAR1 | |
| SCHEMBL12465976 | 0.80 | MAPT (0.52) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12465722 | 0.80 | MAPT (0.60) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL15451616 | 0.79 | LPAR1 (0.68) | MAPTKDM4EALDH1A1HPGDLPAR1 | |
| SCHEMBL25401241 | 0.79 | MAPT (0.57) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12465689 | 0.77 | MAPT (0.51) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL4037272 | 0.77 | MAPT (0.54) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12465621 | 0.77 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL12466067 | 0.76 | MAPT (0.61) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |