Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401241 | 0.87 | MAPT (0.57) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 | |
| SCHEMBL4037272 | 0.85 | MAPT (0.54) | MAPTKDM4ESMN1; SMN2L3MBTL1LPAR1 | |
| SCHEMBL12465621 | 0.85 | MAPT (0.56) | MAPTKDM4EHTTSMN1; SMN2LPAR1 | |
| SCHEMBL12465757 | 0.85 | MAPT (0.56) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 | |
| SCHEMBL12466067 | 0.84 | MAPT (0.61) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 | |
| SCHEMBL2761636 | 0.84 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 | |
| SCHEMBL4035675 | 0.83 | MAPT (0.67) | MAPTKDM4EHTTSMN1; SMN2LPAR1 | |
| SCHEMBL12465748 | 0.83 | MAPT (0.54) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 | |
| SCHEMBL4034870 | 0.82 | MAPT (0.52) | MAPTKDM4EHTTSMN1; SMN2LPAR1 | |
| SCHEMBL3710978 | 0.82 | MAPT (0.52) | MAPTKDM4ESMN1; SMN2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |