Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 14/20 | 0.40 |
| ▸ | F7 | P08709 | 14/20 | 0.40 |
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027843 | 0.86 | F11 (0.42) | F11F7F10SCN3AIP6K1 | |
| SCHEMBL11023614 | 0.85 | F7 (0.45) | F11F7F10SCN3A | |
| SCHEMBL11028289 | 0.84 | SCN2B (0.43) | F11F7F10SCN3ASCN9A | |
| SCHEMBL11025560 | 0.83 | SCN9A (0.43) | F11F7F10SCN9ASCN5A | |
| SCHEMBL11026899 | 0.83 | F11 (0.45) | F11F7F10SCN3ASCN9A | |
| SCHEMBL11023480 | 0.83 | F11 (0.45) | F11F7F10SCN3A | |
| SCHEMBL11024812 | 0.82 | IP6K1 (0.41) | F11F7F10SCN3AIP6K1 | |
| SCHEMBL11024124 | 0.80 | F11 (0.43) | F11F7F10SCN9A | |
| SCHEMBL11025590 | 0.78 | F11 (0.43) | F11F7F10SCN3A | |
| SCHEMBL11940897 | 0.78 | F11 (0.42) | F11F7F10SCN3AIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668165-A1 | NOVEL TETRAHYDROQUINOLINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101068-A1 | NOVEL TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-02 | — | — | WO | disclosed |