Iodide

Iodide

SCHEMBL12466756

C1=CNc2ccccc2C=C1.I

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34259 0.98 GAA (0.48) GAAMAPT
Water SCHEMBL4672877 0.95 GAA (0.46) GAAMAPT
Ammonia Solution, Strong SCHEMBL4151802 0.95 GAA (0.46) GAAMAPT
SCHEMBL29181632 0.95 GAA (0.46) GAAMAPT
SCHEMBL8654087 0.95 GAA (0.46) GAAMAPT
SCHEMBL1787947 0.95 GAA (0.46) GAAMAPT
Hydrochloric Acid SCHEMBL160640 0.95 GAA (0.46) GAAMAPT
Water SCHEMBL16465946 0.95 GAA (0.46) GAAMAPT
Bromide SCHEMBL10654286 0.95 GAA (0.46) GAAMAPT
SCHEMBL8654084 0.95 GAA (0.46) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611427-A2 MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT& xA; Arena Pharmaceuticals, Inc. (US) 2013-07-10 EP disclosed
WO-2012030927-A2 MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT ARENA PHARMACEUTICALS, INC. (US) 2012-03-08 WO disclosed