Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 15/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596313 | 0.96 | ICMT (0.70) | ICMTALDH1A1MAPT | |
| SCHEMBL4028704 | 0.90 | ICMT (0.83) | ICMTALDH1A1MAPT | |
| SCHEMBL12110880 | 0.90 | ICMT (0.61) | ICMTALDH1A1MAPT | |
| SCHEMBL12466755 | 0.90 | ICMT (0.61) | ICMTALDH1A1MAPT | |
| SCHEMBL12466863 | 0.87 | ICMT (0.59) | ICMTALDH1A1MAPT | |
| SCHEMBL1304833 | 0.86 | ICMT (0.68) | ICMTALDH1A1MAPT | |
| SCHEMBL12110882 | 0.86 | ICMT (0.68) | ICMTALDH1A1MAPT | |
| SCHEMBL14596318 | 0.86 | ICMT (0.63) | ICMTALDH1A1MAPT | |
| SCHEMBL12466742 | 0.85 | ICMT (0.69) | ICMTALDH1A1MAPT | |
| SCHEMBL14596315 | 0.84 | ICMT (0.62) | ICMTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592173-B2 | Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130084573-A1 | Cancer Diagnosis by Measuring Polyisoprenylated Methylated Protein Methyl Esterase Activity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-04-04 | — | — | US | disclosed |
| WO-2012102773-A2 | CANCER DIAGNOSIS BY MEASURING POLYISOPRENYLATED METHYLATED PROTEIN METHYL ESTERASE ACTIVITY | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2012-08-02 | — | — | WO | disclosed |