Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 9/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466760 | 0.83 | HDAC1 (0.43) | HDAC1HDAC6KDM1AKDM4EMAPT | |
| SCHEMBL12466716 | 0.80 | KDM1A (0.44) | KDM1AATMKDM4EMAPTKMT2A | |
| SCHEMBL6714534 | 0.80 | MAPT (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12466637 | 0.79 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064545 | 0.72 | HDAC3 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064543 | 0.72 | HDAC3 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064551 | 0.71 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064587 | 0.71 | TP53 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064588 | 0.71 | TP53 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15064552 | 0.71 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012102965-A1 | 4-ANILINOFURO[2,3-b]QUINOLINE DERIVATIVES, THEIR PREPARATION PROCESSES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KAOHSIUNG MEDICAL UNIVERSITY (CN) | 2012-08-02 | — | — | WO | disclosed |