Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467226 | 1.00 | GHSR (0.81) | GHSR | |
| SCHEMBL19856984 | 1.00 | GHSR (0.81) | GHSR | |
| SCHEMBL12467281 | 0.96 | GHSR (0.82) | GHSR | |
| SCHEMBL12467238 | 0.96 | GHSR (0.82) | GHSR | |
| SCHEMBL15280579 | 0.90 | GHSR (1.00) | GHSR | |
| SCHEMBL743812 | 0.90 | GHSR (1.00) | GHSR | |
| SCHEMBL19856986 | 0.89 | GHSR (1.00) | GHSR | |
| SCHEMBL743420 | 0.89 | GHSR (1.00) | GHSR | |
| SCHEMBL12467232 | 0.88 | GHSR (0.76) | GHSR | |
| SCHEMBL19856983 | 0.88 | GHSR (0.76) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616070-B1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2018-02-14 | — | — | EP | claimed |
| US-8546435-B2 | Triazole derivatives with improved receptor activity and bioavailability properties as ghrelin antagonists of growth hormone secretagogue receptors | AETERNA ZENTARIS GMBH (DE) | 2013-10-01 | — | — | US | claimed |
| EP-2616070-A1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | Æterna Zentaris GmbH (DE) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035124-A1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2012-03-22 | — | — | WO | claimed |
| EP-2616070-B1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2018-02-14 | — | — | EP | disclosed |
| US-8546435-B2 | Triazole derivatives with improved receptor activity and bioavailability properties as ghrelin antagonists of growth hormone secretagogue receptors | AETERNA ZENTARIS GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| EP-2616070-A1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | Æterna Zentaris GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035124-A1 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2012-03-22 | — | — | WO | disclosed |