Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138654 | 0.90 | HPGD (0.39) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL13621280 | 0.89 | ATM (0.45) | MAPTATMGAARAB9AHTT | |
| SCHEMBL8738575 | 0.85 | MAPT (0.42) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL9150315 | 0.82 | CYP3A4 (0.44) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL13901387 | 0.80 | HPGD (0.40) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL30567467 | 0.80 | ALDH1A1 (0.52) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL85405 | 0.80 | ALDH1A1 (0.52) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL24280133 | 0.80 | TSHR (0.43) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 | |
| SCHEMBL18910459 | 0.80 | HPGD (0.42) | MAPTATMMEN1KMT2AGAA | |
| SCHEMBL18649452 | 0.79 | DRD3 (0.42) | MAPTCYP3A4TAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133294-A2 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-11-05 | — | — | WO | disclosed |