Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | SCN4A | P35499 | 1/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493239 | 0.82 | EPHB4 (0.53) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL11170743 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL11170750 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL6455411 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL9354277 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAKMT2ACYP2C9 | |
| SCHEMBL9354265 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAKMT2ACYP2C9 | |
| SCHEMBL30051979 | 0.78 | MAPT (0.67) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL4333871 | 0.78 | POLB (0.60) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL6430240 | 0.78 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MAPTLMNASCN3A | |
| SCHEMBL27479697 | 0.78 | NPC1 (0.64) | ALDH1A1MAPTLMNAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140956-A1 | PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2020-07-09 | — | — | WO | disclosed |
| WO-2012103113-A1 | PYRAZINE AND IMIDAZOLIDINE DERIVATIVES AND THEIR USES TO TREAT HEPATITIS C | GILEAD PHARMASSET, LLC (US) | 2012-08-02 | — | — | WO | disclosed |