Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ACP1 | P24666 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467969 | 0.80 | CYP19A1 (0.47) | CYP3A4SLC2A1DHODHLMNASMN1; SMN2 | |
| SCHEMBL17688770 | 0.69 | ACP1 (0.65) | CYP3A4LMNASMN1; SMN2ACP1KDM4E | |
| SCHEMBL15237514 | 0.69 | CYP1A2 (0.58) | SMN1; SMN2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL484152 | 0.68 | CYP3A4 (0.54) | CYP3A4LMNASMN1; SMN2ACP1KDM4E | |
| SCHEMBL6534399 | 0.68 | CYP3A4 (0.54) | CYP3A4LMNASMN1; SMN2ACP1KDM4E | |
| SCHEMBL28459418 | 0.68 | DHODH (0.74) | CYP3A4DHODHLMNASMN1; SMN2KDM4E | |
| SCHEMBL13568539 | 0.68 | CYP3A4 (0.53) | CYP3A4DHODHLMNASMN1; SMN2ACP1 | |
| SCHEMBL14696946 | 0.66 | LMNA (0.75) | CYP3A4DHODHLMNASMN1; SMN2ACP1 | |
| SCHEMBL12324217 | 0.66 | MAPT (0.54) | CYP3A4LMNASMN1; SMN2ACP1KDM4E | |
| SCHEMBL483403 | 0.66 | CYP3A4 (0.48) | CYP3A4DHODHLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | MAPT, APP, PSEN1 | CYP3A4 4408/4885SLC2A1 2076/4885DHODH 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.