Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454457 | 0.98 | LPAR3 (0.45) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL14359444 | 0.87 | LPAR3 (0.41) | LPAR3LPAR2LPAR1CES1CES2 | |
| SCHEMBL28353706 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL2808705 | 0.77 | CES1 (0.42) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL30634500 | 0.77 | CES1 (0.47) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL11596808 | 0.76 | LPAR3 (0.39) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL4939579 | 0.76 | LPAR3 (0.43) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL29435127 | 0.76 | MEN1 (0.41) | CES1MEN1THRBHTTKMT2A | |
| SCHEMBL8769729 | 0.75 | CES1 (0.45) | LPAR3LPAR2LPAR1CES1CA12 | |
| SCHEMBL13456958 | 0.75 | CES1 (0.45) | LPAR3LPAR2LPAR1CES1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038538-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE QUATERNARY AMMONIUM ESTER AND AT LEAST ONE SOLUBLE SALT OF DIVALENT METALS, AND PROCESS USING THE SAID COMPOSITION | L'OREAL (FR) | 2012-03-29 | — | — | WO | claimed |