Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468489 | 0.81 | SOAT1 (0.34) | KDM4ESOAT1 | |
| SCHEMBL12468567 | 0.81 | SOAT1 (0.34) | SOAT1 | |
| SCHEMBL12468514 | 0.74 | SOAT1 (0.30) | SOAT1 | |
| SCHEMBL16142354 | 0.68 | LTA4H (0.50) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| SCHEMBL23611278 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| SCHEMBL499333 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| SCHEMBL13707354 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| SCHEMBL1105086 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| Alpha-Terthienyl SCHEMBL147274 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 | |
| SCHEMBL2742433 | 0.67 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012049167-A1 | NOVEL OLIGOTHIOPHENE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR USES | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2012-04-19 | — | — | WO | claimed |
| WO-2012049167-A1 | NOVEL OLIGOTHIOPHENE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR USES | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2012-04-19 | — | — | WO | disclosed |