Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468550 | 0.81 | WRN (0.35) | SMN1; SMN2NPC1RAB9ASOAT1 | |
| SCHEMBL13788344 | 0.80 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9ASOAT1 | |
| SCHEMBL12468465 | 0.78 | CHRM2 (0.43) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12468310 | 0.77 | CHRM2 (0.43) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12468476 | 0.77 | CHRM2 (0.43) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12180495 | 0.77 | APP (0.47) | SMN1; SMN2NPC1RAB9ASOAT1 | |
| SCHEMBL12468569 | 0.77 | CHRM2 (0.43) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12468469 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1177920 | 0.76 | NPC1 (0.30) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14907591 | 0.73 | RAB9A (0.36) | SMN1; SMN2NPC1RAB9ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012049167-A1 | NOVEL OLIGOTHIOPHENE DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR USES | UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II (FR) | 2012-04-19 | — | — | WO | disclosed |