Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 17/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462359 | 0.86 | TTK (0.42) | TTKSYKMAPK10MAPK8 | |
| SCHEMBL12468486 | 0.81 | TTK (0.58) | TTKCYP3A4 | |
| SCHEMBL462242 | 0.80 | USP2 (0.34) | TTKCYP3A4SYK | |
| SCHEMBL462654 | 0.79 | PDE4A (0.36) | TTKCYP3A4SYK | |
| SCHEMBL462101 | 0.78 | TTK (0.42) | TTKMAPK10MAPK8 | |
| SCHEMBL463364 | 0.75 | TTK (0.40) | TTKMAPK10MAPK8 | |
| SCHEMBL10279265 | 0.74 | TTK (0.61) | TTKCYP3A4 | |
| SCHEMBL461869 | 0.74 | TTK (0.55) | TTKCYP3A4SYK | |
| SCHEMBL15560602 | 0.73 | TTK (0.54) | TTK | |
| SCHEMBL17416363 | 0.72 | TTK (0.60) | TTKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | claimed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | claimed |