Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 11/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462101 | 0.86 | TTK (0.42) | TTKMAPK8MAPK10TYK2 | |
| SCHEMBL17560054 | 0.81 | TTK (0.46) | TTKMAPK8MAPK10 | |
| SCHEMBL462359 | 0.78 | TTK (0.42) | TTKMAPK8MAPK10 | |
| SCHEMBL463363 | 0.77 | TTK (0.66) | TTK | |
| SCHEMBL463164 | 0.76 | TTK (0.50) | TTK | |
| SCHEMBL462242 | 0.75 | USP2 (0.34) | TTKCHRM4BTK | |
| SCHEMBL12468487 | 0.75 | TTK (0.38) | TTKMAPK8MAPK10 | |
| SCHEMBL462654 | 0.75 | PDE4A (0.36) | TTKCHRM4BTKTYK2 | |
| SCHEMBL470029 | 0.74 | TTK (0.60) | TTK | |
| SCHEMBL15554967 | 0.74 | TTK (0.50) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | claimed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | claimed |