Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | BCR | P11274 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043934 | 0.84 | KAT6A (0.55) | KAT6AABL1BCRNTRK1PDPK1 | |
| SCHEMBL30850854 | 0.82 | KAT6A (0.60) | KAT6AABL1BCRHPGDNTRK1 | |
| SCHEMBL939202 | 0.82 | KAT6A (0.60) | KAT6AABL1BCRHPGDNTRK1 | |
| SCHEMBL2303493 | 0.81 | KAT6A (0.55) | KAT6AABL1BCRNTRK1PDPK1 | |
| SCHEMBL6031253 | 0.81 | KAT6A (0.55) | KAT6AABL1BCRNTRK1PDPK1 | |
| SCHEMBL3741524 | 0.80 | KAT6A (0.55) | KAT6AABL1BCRHPGDNTRK1 | |
| SCHEMBL2733047 | 0.80 | KAT6A (0.61) | KAT6AABL1BCRHPGDNTRK1 | |
| SCHEMBL5078585 | 0.77 | KAT6A (0.49) | KAT6AHPGDNTRK1PTGDR2 | |
| SCHEMBL15805858 | 0.76 | PDPK1 (0.72) | KAT6ANTRK1PDPK1HDAC2PTGDR2 | |
| SCHEMBL28461611 | 0.75 | SIRT2 (0.70) | KAT6AHPGDNTRK1HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SERPINB1, CTSC, HPN | KAT6A 3545/4885ABL1 995/4885BCR 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.