⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871580 | 0.80 | — | — | |
| SCHEMBL12799428 | 0.77 | MEN1 (0.78) | — | |
| SCHEMBL787737 | 0.77 | — | — | |
| SCHEMBL24333630 | 0.77 | FAAH (0.58) | — | |
| SCHEMBL23656833 | 0.76 | CA12 (0.40) | — | |
| SCHEMBL10203505 | 0.76 | — | — | |
| SCHEMBL2386786 | 0.75 | — | — | |
| SCHEMBL13819826 | 0.75 | MEN1 (0.58) | — | |
| SCHEMBL20024761 | 0.75 | MEN1 (0.46) | — | |
| SCHEMBL11564245 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857597-B2 | Lipo-glycopeptide cleavable derivatives and uses thereof | INSMED INCORPORATED (US) | 2024-01-02 | — | — | US | disclosed |
| US-9840537-B2 | Selective delivery molecules and methods of use | AVELAS BIOSCIENCES, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
| CN-102908624-A | Pharmaceutical product comprising a muscarinic receptor antagonist and a beta2-adrenoceptor agonist | ASTRAZENECA SWEDEN AB | 2013-02-06 | — | — | CN | disclosed |
| CN-102088976-B | Comprising a muscarinic receptor antagonist and beta2-pharmaceutical products of adrenoreceptor agonists | ASTRAZENECA AB | 2012-12-26 | — | — | CN | disclosed |
| CN-101678005-B | Combination of a muscarinic receptor antagonist and a beta-2 adrenergic receptor agonist | ARGENTA DISCOVERY LTD | 2012-10-31 | — | — | CN | disclosed |
| CN-102625808-A | Spirocyclic amide derivatives | ASTRAZENECA AB | 2012-08-01 | — | — | CN | disclosed |
| CN-102202664-A | Pharmaceutical product comprising a muscarinic receptor antagonist and a beta-2-adrenoceptor agonist | ASTRAZENECA AB | 2011-09-28 | — | — | CN | disclosed |
| CN-102124003-A | Benzoxazinone derivatives as beta 2 adrenoreceptor antagonists for the treatment of respiratory diseases | ASTRAZENECA AB | 2011-07-13 | — | — | CN | disclosed |
| CN-102088976-A | Comprising a muscarinic receptor antagonist and beta2-pharmaceutical products of adrenoreceptor agonists | ASTRAZENECA AB | 2011-06-08 | — | — | CN | disclosed |
| EP-2315589-A1 | PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST | AstraZeneca AB (SE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2011012896-A2 | COMPOUNDS - 801 | ASTRAZENECA AB (SE) | 2011-02-03 | — | — | WO | disclosed |
| EP-1732880-B1 | ASSAYS FOR AMPHETAMINE AND METHAMPHETAMINE | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20100152099-A1 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA | ENSEMBLE THERAPEUTICS CORPORATION | 2010-06-17 | — | — | US | disclosed |
| CN-101678005-A | Combination of a muscarinic receptor antagonist and a beta-2 adrenergic receptor agonist | ARGENTA DISCOVERY LTD | 2010-03-24 | — | — | CN | disclosed |
| WO-2010022249-A2 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA | ENSEMBLE DISCOVERY CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |
| CN-101652137-A | Combinations of beta- 2 -adrenoceptor agonistic benzothiazolone | ASTRAZENECA AB SE | 2010-02-17 | — | — | CN | disclosed |
| CN-101605770-A | Salt 668 | ASTRAZENECA AB (SE) | 2009-12-16 | — | — | CN | disclosed |
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |
| CN-101282950-A | Novel benzothiazolone derivatives | ASTRAZENECA AB (SE) | 2008-10-08 | — | — | CN | disclosed |