SCHEMBL12468677

SCHEMBL12468677

C=CC(=O)OC(CC)C(CCC)[SiH](OC)OC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
HPGD P15428 1/20 0.35
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21632818 0.91 TSHR (0.41) TSHRHPGDTHRB
SCHEMBL18051042 0.81 TSHR (0.38) TSHRHPGD
SCHEMBL26841668 0.80 TSHR (0.45) TSHRHPGDTHRB
SCHEMBL193209 0.79 TSHR (0.38) TSHRHPGDTHRB
SCHEMBL23493964 0.77 TSHR (0.42) TSHRHPGDTHRB
SCHEMBL139741 0.75 TSHR (0.37) TSHRHPGDTHRB
SCHEMBL23493896 0.73 TSHR (0.42) TSHRHPGDTHRB
SCHEMBL12468571 0.73 TSHR (0.46) TSHRHPGDTHRB
SCHEMBL12468572 0.73 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL23494246 0.73 TSHR (0.42) TSHRHPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP disclosed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO disclosed
EP-2785726-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS Dow Corning Corporation (US) 2014-10-08 EP disclosed
EP-2762482-A1 Process for purifying an acryloyloxysilane Dow Corning Corporation (US) 2014-08-06 EP disclosed
EP-2621936-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2013-08-07 EP disclosed
WO-2013081820-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW CORNING CORPORATION (US) 2013-06-06 WO disclosed
WO-2012050761-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2012-04-19 WO disclosed