SCHEMBL193209

SCHEMBL193209

C=CC(=O)OC(CCC)[SiH](OC)OC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 3/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
THRA P10827 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12468571 0.90 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28214426 0.90 TSHR (0.33) TSHRHPGD
SCHEMBL23174785 0.87 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL139741 0.86 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL2853098 0.85 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL8007977 0.83 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28030112 0.82 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3750794 0.81 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL12468677 0.79 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL963718 0.78 TSHR (0.34) TSHRALDH1A1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3577176-B1 LOW TEMPERATURE CURABLE ADHESIVE COMPOSITIONS SIMPSON STRONG TIE CO INC (US) 2024-10-23 EP claimed
CN-115772379-A UV (ultraviolet) delayed curing double-component polyurethane adhesive and preparation method thereof 韦尔通(厦门)科技股份有限公司 2023-03-10 CN claimed
CN-113201280-A Release silicone oil capable of improving PEK substrate anchorage and preparation method thereof 惠州市永卓科技有限公司 2021-08-03 CN claimed
CN-107075304-B High gain durable anti-reflective coating 第一阳光公司 2020-10-16 CN claimed
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
WO-2017040514-A1 ABSORBENT BINDER COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2017-03-09 WO claimed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
US-9416300-B2 Low temperature curable adhesive compositions SIMPSON STRONG-TIE COMPANY, INC. (US) 2016-08-16 US claimed
JP-2005533921-A 2005-11-10 JP claimed
EP-1525010-A1 ABSORBENT BINDER COMPOSITION, METHOD OF MAKING IT, AND ARTICLES INCORPORATING IT Kimberly-Clark Worldwide, Inc. (US) 2005-04-27 EP claimed
US-6737491-B2 CONTAINING COPOLYMER HAVING ACRYLIC ESTER WITH TRIALKOXY-SILANE FUNCTIONALITY; CAPABLE OF MOISTURE INDUCED SELF-CROSSLINKING KIMBERLY-CLARK WORLDWIDE, INC. 2004-05-18 US claimed
WO-2004011046-A1 ABSORBENT BINDER COMPOSITION, METHOD OF MAKING IT, AND ARTICLES INCORPORATING IT KIMBERLY-CLARK WORLDWIDE, INC. (US) 2004-02-05 WO claimed
US-20040019169-A1 ABSORBENT BINDER COMPOSITION AND METHOD OF MAKING SAME KIMBERLY-CLARK WORLDWIDE, INC. 2004-01-29 US claimed
EP-1360254-A2 ABSORBENT, LUBRICIOUS COATING AND ARTICLES COATED THEREWITH Kimberly-Clark Worldwide, Inc. (US) 2003-11-12 EP claimed
US-6610793-B1 Biodegradable absorbent material crosslinks into a gel structure upon exposure to moisture; PEO grafted with a moiety which contains a trialkoxysilane functional group; reactive extrusion; methacryloxypropyl trimethoxysilane KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-26 US claimed
US-6596402-B2 Contacting the article with a copolymer comprising a water soluble base polymer having graft polymerized thereto organic moiety that includes a group that reacts with water to form a silanol group; curing the copolymer KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-22 US claimed
US-20020132540-A1 Absorbent, lubricious coating and articles coated therewith KIMBERLY-CLARK WORLDWIDE, INC. 2002-09-19 US claimed
WO-2002053664-A2 ABSORBENT, LUBRICIOUS COATING AND ARTICLES COATED THEREWITH KIMBERLY-CLARK WORLDWIDE, INC. (US) 2002-07-11 WO claimed