⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meglutol SCHEMBL8718194 | 0.85 | HMGCR (1.00) | — | |
| Meglutol SCHEMBL28443 | 0.85 | HMGCR (1.00) | — | |
| Bicarbonate SCHEMBL29012528 | 0.79 | HMGCR (0.50) | — | |
| Mevalonic Acid SCHEMBL120276 | 0.79 | HMGCR (0.67) | — | |
| Mevalonic Acid SCHEMBL120275 | 0.79 | HMGCR (0.67) | — | |
| Mevalonic Acid SCHEMBL8854071 | 0.79 | HMGCR (0.67) | — | |
| Mevalonic Acid SCHEMBL18376074 | 0.79 | HMGCR (0.67) | — | |
| SCHEMBL29229017 | 0.78 | — | — | |
| SCHEMBL12323030 | 0.78 | — | — | |
| SCHEMBL380313 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165925-B1 | METHODS FOR THE DIAGNOSIS OF COLORECTAL CANCER | MED LIFE DISCOVERIES LP (CA) | 2021-09-08 | — | — | EP | disclosed |
| US-11079385-B2 | Serum-based biomarkers of pancreatic cancer and uses thereof for disease detection and diagnosis | MED-LIFE DISCOVERIES LP (CA) | 2021-08-03 | — | — | US | disclosed |
| US-20210041444-A1 | METHODS FOR DIAGNOSING A COLORECTAL CANCER (CRC) HEALTH STATE OR CHANGE IN CRC HEALTH STATE, OR FOR DIAGNOSING RISK OF DEVELOPING CRC OR THE PRESENCE OF CRC IN A SUBJECT | PHENOMENOME DISCOVERIES INC. (CA) | 2021-02-11 | — | — | US | disclosed |
| US-20210033614-A1 | SERUM-BASED BIOMARKERS OF PANCREATIC CANCER AND USES THEREOF FOR DISEASE DETECTION AND DIAGNOSIS | MED LIFE DISCOVERIES LP (CA) | 2021-02-04 | — | — | US | disclosed |
| US-10697969-B2 | Methods for diagnosing a colorectal cancer (CRC) health state or change in CRC health state, or for diagnosing risk of developing CRC or the presence of CRC in a subject | MED-LIFE DISCOVERIES LP (CA) | 2020-06-30 | — | — | US | disclosed |
| US-10656155-B2 | Serum-based biomarkers of pancreatic cancer and uses thereof for disease detection and diagnosis | MED-LIFE DISCOVERIES LP (CA) | 2020-05-19 | — | — | US | disclosed |
| US-20190004049-A1 | SERUM-BASED BIOMARKERS OF PANCREATIC CANCER AND USES THEREOF FOR DISEASE DETECTION AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2019-01-03 | — | — | US | disclosed |
| US-10024857-B2 | Serum-based biomarkers of pancreatic cancer and uses thereof for disease detection and diagnosis | MED-LIFE DISCOVERIES LP (CA) | 2018-07-17 | — | — | US | disclosed |
| EP-2770328-B1 | Method to diagnose pancreatic cancer | PHENOMENOME DISCOVERIES INC (CA) | 2017-12-27 | — | — | EP | disclosed |
| EP-2483697-B2 | METHOD TO DIAGNOSE PANCREATIC CANCER | PHENOMENOME DISCOVERIES INC (CA) | 2017-07-05 | — | — | EP | disclosed |
| EP-2459510-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | Phenomenome Discoveries Inc. (CA) | 2012-06-06 | — | — | EP | disclosed |
| US-20120136057-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2012-05-31 | — | — | US | disclosed |
| WO-2011038509-A1 | SERUM-BASED BIOMARKERS OF PANCREATIC CANCER AND USES THEREOF FOR DISEASE DETECTION AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011011882-A1 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS | PHENOMENOME DISCOVERIES INC. (CA) | 2011-02-03 | — | — | WO | disclosed |
| US-20080255764-A1 | Methods for the Diagnosis of Colorectal Cancer and Ovarian Cancer by the Measurement of Vitamin E-Related Metabolites | PHENOMENOME DISCOVERIES INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| EP-1931995-A2 | METHODS FOR THE DIAGNOSIS OF COLORECTAL CANCER AND OVARIAN CANCER HEALTH STATES | Phenomenome Discoveries Inc. (CA) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007030928-A2 | METHOD FOR THE DIAGNOSIS OF COLORECTAL CANCER AND OVARIAN CANCER BY THE MEASUREMENT OF VITAMIN E-RELATED METABOLITES | PHENOMENOME DISCOVERIES INC. (CA) | 2007-03-22 | — | — | WO | disclosed |
| EP-1052258-B1 | PROCESS FOR PRODUCING BETA-HYDROXY-GAMMA-BUTYROLACTONE DERIVATIVES AND BETA-(METH)ACRYLOYLOXY-GAMMA-BUTYROLACTONE DERIVATIVES | MITSUBISHI RAYON CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6313321-B1 | Process for preparing β-hydroxy-γ-butyrolactones and β-(meth)acryloyloxy-γ-butrolactones | MITSUBISHI RAYON CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1052258-A1 | PROCESS FOR PRODUCING BETA-HYDROXY-GAMMA-BUTYROLACTONE DERIVATIVES AND BETA-(METH)ACRYLOYLOXY-GAMMA-BUTYROLACTONE DERIVATIVES | Mitsubishi Rayon Co., Ltd. (JP) | 2000-11-15 | — | — | EP | disclosed |