Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 11/20 | 1.00 |
| ▸ | HTR3A | P46098 | 5/20 | 0.60 |
| ▸ | HTR1D | P28221 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aerugine SCHEMBL29926829 | 1.00 | HTR2B (1.00) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| Aerugine SCHEMBL12468918 | 1.00 | HTR2B (1.00) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL1268305 | 0.82 | HTR2B (0.69) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL1268310 | 0.82 | HTR2B (0.69) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL1266688 | 0.80 | HTR2B (0.66) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL1266690 | 0.80 | HTR2B (0.66) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL19307988 | 0.77 | HTR2B (0.62) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL15423025 | 0.74 | HTR2B (0.57) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL1686982 | 0.73 | HTR2B (0.76) | HTR2BHTR3AHTR1DHTR7HTR2C | |
| SCHEMBL30608416 | 0.73 | HTR2B (0.76) | HTR2BHTR3AHTR1DHTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115177616-B | Application of streptomyces bricorubidus extract in preparation of anti-aging product | 中国农业科学院农产品加工研究所 | 2022-11-11 | — | — | CN | disclosed |
| CN-115177616-A | Application of streptomyces bricorubidus extract in preparation of anti-aging product | 中国农业科学院农产品加工研究所 | 2022-10-14 | — | — | CN | disclosed |
| US-9751847-B2 | Methods and compositions related to neuroactive thiazoline compounds | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-01-16 | — | — | US | disclosed |
| WO-2012051502-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | TACR2, TACR3, TACR1 | HTR2B 58/4885HTR3A 41/4885HTR1D 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.