Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524385 | 0.90 | EPHX1 (0.50) | POLBEPHX2MMP2MMP8HPGD | |
| SCHEMBL12469141 | 0.88 | EPHX2 (0.42) | POLBEPHX2MMP2MMP8HPGD | |
| SCHEMBL28515431 | 0.80 | EPHX2 (0.37) | POLBEPHX2MMP2MMP8HPGD | |
| SCHEMBL27006607 | 0.73 | EPHX2 (0.51) | POLBEPHX2HPGDLMNAEPHX1 | |
| SCHEMBL24307260 | 0.72 | HPGD (0.44) | POLBEPHX2MMP2MMP8HPGD | |
| SCHEMBL12469142 | 0.71 | MAPT (0.33) | POLBEPHX2HPGDMAPT | |
| SCHEMBL30673977 | 0.71 | EPHX1 (0.54) | EPHX2MMP2MMP8HPGDEPHX1 | |
| SCHEMBL13667376 | 0.71 | EPHX1 (0.48) | EPHX2MMP2MMP8HPGDEPHX1 | |
| SCHEMBL28668886 | 0.70 | HDAC4 (0.38) | MMP8 | |
| SCHEMBL12020314 | 0.70 | HPGD (0.46) | POLBEPHX2MMP2MMP8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |