Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469141 | 0.77 | EPHX2 (0.42) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL28515431 | 0.74 | EPHX2 (0.37) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL12469140 | 0.71 | POLB (0.39) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL23663375 | 0.69 | EPHX2 (0.39) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL13667376 | 0.66 | EPHX1 (0.48) | MAPTEPHX2HPGD | |
| SCHEMBL30421849 | 0.64 | SSTR4 (0.41) | EPHX2 | |
| SCHEMBL28524385 | 0.63 | EPHX1 (0.50) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL24307260 | 0.63 | HPGD (0.44) | MAPTPOLBEPHX2HPGD | |
| SCHEMBL3620376 | 0.63 | HSD11B1 (0.49) | EPHX2HPGD | |
| SCHEMBL30673977 | 0.62 | EPHX1 (0.54) | MAPTEPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |