Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469667 | 0.96 | BTK (0.43) | BTKFLT3CSNK1A1TYRO3DYRK1B | |
| Aniline SCHEMBL12469012 | 0.94 | BTK (0.42) | BTKFLT3CSNK1A1TYRO3DYRK1B | |
| SCHEMBL12469437 | 0.93 | BTK (0.43) | BTKFLT3CSNK1A1TYRO3DYRK1B | |
| SCHEMBL12469164 | 0.86 | CSF1R (0.40) | BTKFLT3CSNK1A1TYRO3DYRK1B | |
| SCHEMBL12469187 | 0.84 | BTK (0.47) | BTKFLT3CSNK1A1TYRO3DYRK1B | |
| SCHEMBL12469427 | 0.82 | BTK (0.67) | BTKFLT3PIM1PIM2CSF1R | |
| SCHEMBL12469700 | 0.80 | BTK (0.40) | BTKFLT3PIM1PIM2KDR | |
| SCHEMBL12469863 | 0.79 | BTK (0.42) | BTKFLT3PIM1PIM2PDE3B | |
| SCHEMBL8536469 | 0.79 | CSNK1A1 (0.41) | CSNK1A1TYRO3DYRK1B | |
| SCHEMBL12469532 | 0.79 | BTK (0.42) | BTKFLT3PIM1PIM2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |